心血管病治疗：《Braunwald心脏病学》配套Cardiovascular Therapeutics 下载 pdf 百度网盘 epub 免费 2025 电子版 mobi 在线

This companion to Braunwald's Heart Disease equips you with all of today's most effective therapeutic guidelines and management solutions for the full range of heart disease patients. It reflects the most recent standards for drug management as well as the latest in new technologies. Reorganized to mirror your changing practice, each cardiovascular-problem-based section offers a chapter on pharmacologic treatment (with a minimum of pathophysiology)...a chapter on catheter-based or minimally invasive interventions...and a discussion of surgical options. You'll also find a brand-new chapter on gene therapy and stem cell therapy, plus new chapters on many other rapidly developing areas of practice. The result is an outstanding single-volume source for state-of-the-art, clinically oriented guidance on both common and unusual areas of cardiovascular treatment.

Facilitates the decision-making process clinicians face when choosing among various cardiovascular therapeutic options.

covers the latest concepts in pathophysiology, evaluation, and management of patients with cardiovascular disorders

Addresses pharmacological, interventional, and surgical management approaches for each type of cardiovascular disease, putting advice on the full range of therapeutic options at your disposal.

Keeps you current with brand-new chapters on gene therapy and stem cell therapy * unstable and chronic stable angina * management of unstable angina and non-ST-elevation myocardial infarction * devices for heart failure and arrhythmias * prevention of ischemic disease * the regulatory approval process for new cardiovascular drugs and devices * and more.

Delivers a fully revised section on "Heart Failure" that explores cardiac resynchronization therapy, surgical interventions, ambulatory management, hospital management, and cardiac transplantation and circulatory support devices.

Offers a completely updated section on "Other Cardiovascular Conditions" that addresses issues such as pharmacologic treatment of cardiovascular disease during pregnancy * care for adults with congenital heart disease * treatment of primary pulmonary hypertension * prevention and treatment of infective endocarditis * treatment of pericardial disease * and rehabilitation of the patient with cardiovascular disease.

Reflects a new emphasis on the role of diet and exercise in the management of cardiovascular problems in conformity with ACC/AHA/ESC guidelines.

Color Plates follow page xxiv.

SECTION 1 Decision-Making and Therapeutic Strategies in Cardiovascular Medicine

1. Tools for Assessment of Cardiovascular Tests and Therapies

　　Elliott M. Antman, Robert M. Califf, and

Joel Kupersmith

　　　Interpretation of Diagnostic Tests

　　　Clinical Trials

　　　How to Read and Interpret a Clinical Trial

　　　Meta-Analysis

　　　Cost-Effectiveness Analysis

2. The Use of Cardiovascular Drugs: Pharmacological Principles, 35

Stanley Nattel

　　　Pharmacokinetic Factors

　　　Oral Bioavailability (F)

　　　Volume of Distribution

　　　Protein Binding

　　　Elimination and t1/2

　　　Pharmacodynamic Factors

　　　Dose

　　　Drug Interactions

　　　Pharmacogenomics

3. Gene Therapies and Stem Cell Therapies

　　Gene Therapies for Cardiovascular Diseases: Where We Are and Where We Are Going

Luis G. Melo, Christopher A. Ward, and Victor J. Dzau Overview

　　　Gene Therapies for Myocardial Protection

　　　Gene Therapies for Myocardial Rescue

　　　Gene Therapies for Vascular Protection

　　　Clinical Gene Therapy

　　　Perspectives and Future Directions

Stem Cell Therapy for Cardiovascular Disorders

　　　Kai C. Wollert and Helmut Drexler

　　　Potential Donor Cells

　　　Modes of Cell Delivery

　　　Clinical Application of Stem Cell Therapy

　　　Coronary Artery Disease with No Mechanical Revascularization Option

　　　Ischemic Cardiomyopathy, Chronic Heart Failure

　　　The Foreseeable Future of Cardiovascular Stem Cell Therapy

4. The Process of Regulatory Review for New Cardiovascular Devices

Neal L Muni and Brain D. Zuckerman

Regulatory History of the Device Review Process

　　　The Temple Report and Evolution of the Device Regulatory

　　　Process

　　　Risk, Benefit, and the Product Life Cycle

　　　Ensuring the Safety of Marketed Devices

　　　Conclusion

SECTION 2 Ischemic Heart Disease

5. Pharmacologic Options for Treatment of Ischemic Disease

Jonathan Abrams, John Schroeder, William 14. Frishman, and lane Freedman

The Organic Nitrates

　　　Calcium Channel Blockers

　　　β-Adrenergic Blockers

　　　Thrombosis and Ischemic Cardiovascular Disease

　　　Thrombosis: Future Directions

6. Mechanical Approaches to Percutaneous Coronary Intervention

Jahuna Karha, A. Michael Lincoff, and Stephen G. Ellis

　　　Coronary Angioplasty

　　　Other Devices

　　　Intravascular Imaging Techniques

　　　Summary

7. Treatment with Drug-Eluting Stents

George D. Dangas

　　　Drug-Eluting Stent System

　　　Results of Main Clinical Trials of Approved DES

　　　Clinical Use of DES in Different Patient and Clinical Subsets

　　　In-Stent Restenosis

　　　DES Thrombosis

　　　Adjunctive Pharmacologic Therapy

　　　Future Directions

8. Revascularization Options for Ischemic Heart Disease:

Coronary Artery Bypass Grafting and Percutaneous

Coronary Intervention

Oon C. Ooi, Charles J. Mullany, and Charanjit S. Rihal

　　　Effectiveness of Revascularization: CABG

　　　Effectiveness of Revascularization: PCI

　　　Relative Benefits of PCI and CABG

……

SECTION 3 heart Failure

SECTION 4 Arrhythmias/Conduction Disturbances

SECTION 5 Dyslipoproteinemias/Atherosclerosis

SECTION 6 Hypertension

SECTION 7 Other Cardiovascular Conditions

APPENDIX 1

APPENDIX 2

APPENDIX 3

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"This multi-author book contains comprehensive information on cardiovascular therapeutics, a rapidly changing field. Dr Antman is to be congratulated for bringing together 112 experts in their respective fields who collectively contribute 55 chapters. All aspects of cardiovascular therapeutics are covered." Circulation